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张慧杰

编辑: 吴新    发布日期: 2017-09-06   来源:

张慧杰教师专业简历

姓名

张慧杰

性别

出生年月

1986.05

党派

中共党员

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职称

副教授

民族

最高学位

博士

毕业

北海道大学

联系方式

zhj0502@jiangnan.edu.cn

研究方向

生物材料,药物传递,纳米医学

主要学习工作简历和主要学术兼职

【学习和工作经历】

学习经历:

2010/10–2013/09,日本北海道大学,生命科学院,博士

2007/09–2010/06,四川大学, 国家生物医学材料工程技术研究中心,硕士

2003/09–2007/06,安徽师范大学, 化学与材料科学学院,学士

工作经历:

2017/04-至今,江南大学,药学院,副教授

2013/10-2017/03,江南大学,生物工程学院,糖化学与生物技术教育部重点实验室,副教授

2010/10-2013/09,日本国家材料研究所,生物材料中心,初级研究员

【主要学术兼职】

中国生物材料学会会员

江南大学至善学院特聘指导教师

International Journal of Nanomedicine (一区 IF=4.32), Consulting Editor

Nano Today (一区 IF=13.157),Materials Science and Engineering C (二区IF=3.42)等期刊审稿人

科学研究情况简介

【近年来获得的学术科研成果】

近年来在Nanoscale等期刊发表SCI论文20余篇。应邀为Materials Science and Engineering: C撰写综述文章,系统总结了纳米递送系统提高CpG 寡脱氧核苷酸免疫刺激活性的研究进展。参加包括World Biomaterials Congress在内的国际性学术会议近10次,并与国际同行交流相关研究成果。

【近年来主要研究课题】

[1]教育部“留学回国人员科研启动基金”项目,3万元

[2]江南大学自主科研计划青年基金项目JUSRP11427, 8万元

[3]江苏省自然科学基金青年基金项目BK2014141,20万元

[4]2015年基本科研-重点项目(平台建设)子课题,8.75万元

【近年来主要论文代表作】(*为通讯作者)

1. HJ Zhang, T Yamazaki, CY Zhi, N Hanagata. Identification of a boron nitride nanosphere-binding peptide for the intracellular delivery of CpG oligodeoxynucleotides. Nanoscale. 2012;4(20):6343-6350.(一区IF=7.76)

2. HJ Zhang, DD Huang, CX Yuan, T Yan, SN Feng, H Nakanishi, X-D Gao. Genetically engineered yeast spores as chitosan microspheres for intracellular delivery of immunostimulatory CpG oligodeoxynucleotides. Journal of Controlled Release. (Accepted)(一区IF=7.441)

3.HJ Zhang, CY Zhi, X-D Gao. Polyethyleneimine-functionalized boron nitride nanospheres as an efficient carrier for enhancing the immunostimulatory effect of CpG oligodeoxynucleotides. Nanomedicine: Nanotechnology, Biology and Medicine. 2016;12(2):540. (一区IF=5.671)

4.HJ Zhang, S Chen, CY Zhi, T Yamazaki, N Hanagata. Chitosan-coated boron nitride nanospheres enhance delivery of CpG oligodeoxynucleotides and induction of cytokines. International Journal of Nanomedicine. 2013;8:1783-1793. (一区IF=4.32)

5.HJ Zhang, SN Feng, T Yan, CY Zhi, X-D Gao, N Hanagata. Polyethyleneimine-functionalized boron nitride nanospheres as efficient carriers for enhancing the immunostimulatory effect of CpG oligodeoxynucleotides. International Journal of Nanomedicine. 2015;10:5343-5353. (一区IF=4.32)

6.SN Feng, HJ Zhang*, T Yan, DD Huang, CY Zhi, H Nakanishi *, X-D Gao. Folate-conjugated boron nitride nanospheres for targeted delivery of anticancer drugs. International Journal of Nanomedicine. 2016;11:4573-4582. (一区IF=4.32)

7. HJ Zhang, X-D Gao. Nanodelivery systems for enhancing the immunostimulatory effect of CpG oligodeoxynucleotides. Materials Science and Engineering: C. 2017;70(2):935-946. (二区IF=3.42)

8. HJ Zhang, T Yan, S Xu, SN Feng, DD Huang, M Fujita, X-D Gao. Graphene oxide-chitosan nanocomposites for intracellular delivery of immunostimulatory CpG oligodeoxynucleotides. Materials Science and Engineering: C. 2017;73:144-51.(二区IF=3.42)

9.HJ Zhang, XD Zhu, XL Wang, HS Fan, XD Zhang. Effect of Sintering Processes on Surface Properties and Protein Adsorption of Hydroxyapatite Ceramic Particles. Journal of Inorganic Materials. 2010;25(7):770-774. (四区IF=0.551)

10. T Yan, HJ Zhang*, DD Huang, SN Feng, M Fujita, X-D Gao*. Chitosan-functionalized graphene oxide as potential immunoadjuvant. Nanomaterials.2017;7(3):59(二区IF=2.69)

11.J Wang #, HJ Zhang #, XD Zhu, HS Fan, YJ Fan, XD Zhang. Dynamic competitive adsorption of bone-related proteins on calcium phosphate ceramic particles with different phase composition and microstructure. Journal of Biomedical Materials Research Part B-Applied Biomaterials. 2013;101B(6):1069-1077.(共同一作)(二区IF=2.881)

12.Q Xue, HJ Zhang, M Zhu, Z Pei, H Li, Z Wang, Y Huang, Y Huang, Q Deng, J Zhou, S Du, Q Huang, C Zhi. Photoluminescent Ti3C2 MXene Quantum Dots for Multicolor Cellular Imaging. Advanced Materials. DOI: 10.1002/adma.201604847(一区IF=18.96)

13. S Chen, HJ Zhang, Shi XT, Wu HK, Hanagata N. Microfluidic generation of chitosan/CpG oligodeoxynucleotide nanoparticles with enhanced cellular uptake and immunostimulatory properties. Lab on a Chip. 2014;14(11):1842-1849. (一区IF=5.586)

14.XD Zhu, HJ Zhang, HS Fan, W Li, XD Zhang. Effect of phase composition and microstructure of calcium phosphate ceramic particles on protein adsorption. Acta Biomaterialia. 2010;6(4):1536-1541. (一区IF=6.008)

15.S Chen, HJ Zhang, S Chinnathambi, N Hanagata. Synthesis of novel chitosan–silica/CpG oligodeoxynucleotide nanohybrids with enhanced delivery efficiency. Materials Science and Engineering: C. 2013;33(6):3382-3388. (二区IF=3.42)

16.Q Xue, HJ Zhang, MS Zhu, et al. Hydrothermal synthesis of blue-fluorescent monolayer BN and BCNO quantum dots for bio-imaging probes. RSC Advances. 2016;6(82):79090-79094. (二区IF=3.289)

17.XD Zhu, HJ Zhang, DX Li, HS Fan, XD Zhang. Study on the enhanced protein adsorption of microwave sintered hydroxyapatite nanoceramic particles: Role of microstructure. Journal of Biomedical Materials Research Part B-Applied Biomaterials. 2012;100B(2):516-523. (二区IF=2.881)

18.B Li, HJ Zhang, XL Liao, XD Zhu, HS Fan, XD Zhang. Effects of Microstructure of Calcium Phosphate Ceramics Particles on Protein Adsorption. Chemical Journal of Chinese Universities-Chinese. 2012;33(3):447-452. (四区IF=0.791)

19. S Xu, G-Y Zhang, HJ Zhang, T Kitajima, H Nakanishi, X-D Gao. Effects of Rho1, a small GTPase on the production of recombinant glycoproteins in Saccharomyces cerevisiae. Microbial Cell Factories. 2016;15.(一区IF=3.774)

20.J Kong, ZJ Li, HJ Zhang, X-D Gao, H Nakanishi. Production of encapsulated creatinase using yeast spores. Bioengineered. 2016:1-9. (四区IF=1.87)

21.J Kong, ZJ Li, HJ Zhang, X-D Gao, H Nakanishi. Consecutive hydrolysis of creatinine using creatininase and creatinase encapsulated in Saccharomyces cerevisiae spores. Biotechnol Lett. 2016. (三区IF=1.639)

22.XD Zhu, HS Fan, YM Xiao, DX Li, HJ Zhang, T Luxbacher, XD Zhang. Effect of surface structure on protein adsorption to biphasic calcium-phosphate ceramics in vitro and in vivo. Acta Biomaterialia. 2009;5(4):1311-1318. (一区IF=6.008)

23. 黄丹娣,张慧杰,闫听,冯诗倪,中西秀树,高晓冬. 酿酒酵母孢子作为GLP-1载体的研究。食品与生物技术学报. (已接收)

24. 何曾安, 柳艺石, 张慧杰, 高晓冬, 藤田盛久. 哺乳动物细胞株中表达、分泌重组型免疫球蛋白的监控系统构建。食品与生物技术学报. (已接收)

教学 情况简介

【主讲课程】

本科生:细胞生物学

硕士研究生:高级细胞生物学

【指导硕、博士生研究方向】

教学 情况简介

本科生指导:指导本科生1名。

研究生培养:协助指导博士研究生1人,硕士研究生2人

【以上资料更新日期】20174